8OMK

hKHK-C in complex with ADP & fructose 1-phosphate

Summary for 8OMK

• Entry DOI: 10.2210/pdb8omk/pdb
• Descriptor: Ketohexokinase, 1-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: ketohexokinase, khk, product complex, sugar kinase, sugar binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 69459.84

Authors

Ebenhoch, R.,Pautsch, A. (deposition date: 2023-03-31, release date: 2024-01-10, Last modification date: 2024-01-24)

• Primary citation: Heine, N.,Weber, A.,Pautsch, A.,Gottschling, D.,Upheus, I.,Baur, M.,Ebenhoch, R.,Nosse, B.,Kley, J.; Discovery of BI-9787, a Potent Zwitterionic KHK-Inhibitor with Oral Bioavailability; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.48 Å)