8OME
Crystal structure of hKHK-A in complex with compound-4
Summary for 8OME
| Entry DOI | 10.2210/pdb8ome/pdb |
| Descriptor | Ketohexokinase, compound (3 entities in total) |
| Functional Keywords | ketohexokinase, khk, inhibitor bound, sugar kinase, isoform selectivity, sugar binding protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 133019.61 |
| Authors | Ebenhoch, R.,Pautsch, A. (deposition date: 2023-03-31, release date: 2023-09-27, Last modification date: 2023-10-25) |
| Primary citation | Ebenhoch, R.,Bauer, M.,Romig, H.,Gottschling, D.,Kley, J.T.,Heine, N.,Weber, A.,Uphues, I.,Nar, H.,Pautsch, A. Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design. Acta Crystallogr D Struct Biol, 79:871-880, 2023 Cited by PubMed: 37712434DOI: 10.1107/S2059798323006137 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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