8OME

Crystal structure of hKHK-A in complex with compound-4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004454	molecular_function	ketohexokinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006000	biological_process	fructose metabolic process
A	0009744	biological_process	response to sucrose
A	0009749	biological_process	response to glucose
A	0009750	biological_process	response to fructose
A	0010043	biological_process	response to zinc ion
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0032868	biological_process	response to insulin
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046835	biological_process	carbohydrate phosphorylation
A	0070061	molecular_function	fructose binding
A	0070062	cellular_component	extracellular exosome
A	0070873	biological_process	regulation of glycogen metabolic process
B	0000166	molecular_function	nucleotide binding
B	0004454	molecular_function	ketohexokinase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006000	biological_process	fructose metabolic process
B	0009744	biological_process	response to sucrose
B	0009749	biological_process	response to glucose
B	0009750	biological_process	response to fructose
B	0010043	biological_process	response to zinc ion
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0032868	biological_process	response to insulin
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046835	biological_process	carbohydrate phosphorylation
B	0070061	molecular_function	fructose binding
B	0070062	cellular_component	extracellular exosome
B	0070873	biological_process	regulation of glycogen metabolic process
C	0000166	molecular_function	nucleotide binding
C	0004454	molecular_function	ketohexokinase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006000	biological_process	fructose metabolic process
C	0009744	biological_process	response to sucrose
C	0009749	biological_process	response to glucose
C	0009750	biological_process	response to fructose
C	0010043	biological_process	response to zinc ion
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0032868	biological_process	response to insulin
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0046835	biological_process	carbohydrate phosphorylation
C	0070061	molecular_function	fructose binding
C	0070062	cellular_component	extracellular exosome
C	0070873	biological_process	regulation of glycogen metabolic process
D	0000166	molecular_function	nucleotide binding
D	0004454	molecular_function	ketohexokinase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006000	biological_process	fructose metabolic process
D	0009744	biological_process	response to sucrose
D	0009749	biological_process	response to glucose
D	0009750	biological_process	response to fructose
D	0010043	biological_process	response to zinc ion
D	0016301	molecular_function	kinase activity
D	0016740	molecular_function	transferase activity
D	0032868	biological_process	response to insulin
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0046835	biological_process	carbohydrate phosphorylation
D	0070061	molecular_function	fructose binding
D	0070062	cellular_component	extracellular exosome
D	0070873	biological_process	regulation of glycogen metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19237742","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HW1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PDB","id":"2HW1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19237742","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2HW1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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