8OI0
Structure of the Fmoc-Tau-PAM4 Type 4 amyloid fibril
Summary for 8OI0
Entry DOI | 10.2210/pdb8oi0/pdb |
Related | 8OH2 8OHI 8OHP |
EMDB information | 16886 |
Descriptor | Microtubule-associated protein tau (1 entity in total) |
Functional Keywords | amyloid, tau, helical, cross-beta, fibril, neurodegeneration, fmoc, protein fibril |
Biological source | synthetic construct |
Total number of polymer chains | 24 |
Total formula weight | 39654.46 |
Authors | Wilkinson, M.,Louros, N.,Tsaka, G.,Ramakers, M.,Morelli, C.,Garcia, T.,Gallardo, R.U.,D'Haeyer, S.,Goossens, V.,Audenaert, D.,Thal, D.R.,Ranson, N.A.,Radford, S.E.,Rousseau, F.,Schymkowitz, J. (deposition date: 2023-03-21, release date: 2024-02-21) |
Primary citation | Louros, N.,Wilkinson, M.,Tsaka, G.,Ramakers, M.,Morelli, C.,Garcia, T.,Gallardo, R.,D'Haeyer, S.,Goossens, V.,Audenaert, D.,Thal, D.R.,Mackenzie, I.R.,Rademakers, R.,Ranson, N.A.,Radford, S.E.,Rousseau, F.,Schymkowitz, J. Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15:1028-1028, 2024 Cited by PubMed: 38310108DOI: 10.1038/s41467-024-45429-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
Download full validation report