8OGH

Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis with butylacetylphosphonate (BAP) bound

8OGH の概要

• エントリーDOI: 10.2210/pdb8ogh/pdb
• 分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, [(S)-1-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-1-oxidanyl-ethyl]-butoxy-phosphinic acid, GLYCEROL, ... (7 entities in total)
• 機能のキーワード: complex, inhibitor, thdp, mep-pathway, transferase
• 由来する生物種: Mycobacterium tuberculosis H37Rv; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 129448.61

構造登録者

Gawriljuk, O.V.,Oerlemans, R.,Groves, R.M. (登録日: 2023-03-20, 公開日: 2023-05-10, 最終更新日: 2023-10-25)

• 主引用文献: Gawriljuk, V.O.,Oerlemans, R.,Gierse, R.M.,Jotwani, R.,Hirsch, A.K.H.,Groves, M.R.; Structure of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Synthase in Complex with Butylacetylphosphonate; Crystals, 13:-, 2023; DOI: 10.3390/cryst13050737

実験手法

X-RAY DIFFRACTION (1.6 Å)