8OGE

Structure of cobalt(II) substituted double mutant human carbonic anhydrase II bound to thiocyanate

8OGE の概要

• エントリーDOI: 10.2210/pdb8oge/pdb
• 分子名称: Carbonic anhydrase 2, 4-(HYDROXYMERCURY)BENZOIC ACID, COBALT (II) ION, ... (5 entities in total)
• 機能のキーワード: inhibitor, thiocyanate, cobalt, metal binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29696.70

構造登録者

Silva, J.M.,Cerofolini, L.,Carvalho, A.L.,Ravera, E.,Fragai, M.,Parigi, G.,Macedo, A.L.,Geraldes, C.F.G.C.,Luchinat, C. (登録日: 2023-03-20, 公開日: 2024-02-07)

• 主引用文献: Silva, J.M.,Cerofolini, L.,Carvalho, A.L.,Ravera, E.,Fragai, M.,Parigi, G.,Macedo, A.L.,Geraldes, C.F.G.C.,Luchinat, C.; Elucidating the concentration-dependent effects of thiocyanate binding to carbonic anhydrase.; J.Inorg.Biochem., 244:112222-112222, 2023; PubMed: 37068394; DOI: 10.1016/j.jinorgbio.2023.112222

実験手法

X-RAY DIFFRACTION (1.46 Å)