8OFZ

Molecular Mechanism of trypanosomal AQP2

Summary for 8OFZ

• Entry DOI: 10.2210/pdb8ofz/pdb
• EMDB information: 16864
• Descriptor: Aquaglyceroporin 2, GLYCEROL (2 entities in total)
• Functional Keywords: aquaporin, tetramer, drug uptake, glycerol, membrane protein
• Biological source: Trypanosoma brucei brucei
• Total number of polymer chains: 1
• Total formula weight: 33798.83

Authors

Weyand, S.N.,Matusevicius, M.,Yamashita, K. (deposition date: 2023-03-17, release date: 2024-10-02, Last modification date: 2025-10-22)

• Primary citation: Matusevicius, M.,Corey, R.A.,Gragera, M.,Yamashita, K.,Sprenger, T.,Ungogo, M.A.,Blaza, J.N.,Castro-Hartmann, P.,Chirgadze, D.Y.,Chaitanya Vedithi, S.,Afanasyev, P.,Melero, R.,Warshamanage, R.,Gusach, A.,Carazo, J.M.,Carrington, M.,Blundell, T.L.,Murshudov, G.,Stansfeld, P.,Sansom, M.,de Koning, H.P.,Tate, C.G.,Weyand, S.N.; Insights from aquaporin structures into drug-resistant sleeping sickness; Elife, 2025; DOI: 10.7554/elife.107460.1

Experimental method

ELECTRON MICROSCOPY (3.2 Å)