8KME

CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN INHIBITED WITH SEL2770.

Summary for 8KME

Related PRD IDPRD_000355
DescriptorTHROMBIN, N-ACETYLHIRUDIN, SEL2770, ... (6 entities in total)
Functional Keywordsthrombin, hydrolase-hydrolase inhibitor complex, selectide, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space P00734 P00734
Total number of polymer chains4
Total molecular weight36023.1
Authors
Mochalkin, I.,Tulinsky, A. (deposition date: 1999-03-21, release date: 1999-03-24, Last modification date: 2017-10-04)
Primary citation
Mochalkin, I.,Tulinsky, A.
Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding.
Acta Crystallogr.,Sect.D, 55:785-793, 1999
PubMed: 10089309 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444999000359
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers421.8%20.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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