8KET

Cryo-EM structure of HRD1-SEL1LFL-XTP3B complex

Summary for 8KET

Entry DOI	10.2210/pdb8ket/pdb
EMDB information	37167
Descriptor	E3 ubiquitin-protein ligase synoviolin, Endoplasmic reticulum lectin 1, ANA, ... (6 entities in total)
Functional Keywords	erad, protein degradation, allergen
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	253985.45
Authors	Qian, H.W.,He, J.J. (deposition date: 2023-08-13, release date: 2025-02-19, Last modification date: 2025-09-03)
Primary citation	Guo, L.,Liu, G.,He, J.,Jia, X.,He, Y.,Wang, Z.,Qian, H. Structural insights into the human HRD1 ubiquitin ligase complex Nat Commun, 16:6007-, 2025 Cited by DOI: 10.1038/s41467-025-61143-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation