8KES

Cryo-EM structure of HRD1-SEL1LX3-XTP3B complex in C1 symmetry

Summary for 8KES

• Entry DOI: 10.2210/pdb8kes/pdb
• EMDB information: 37166
• Descriptor: E3 ubiquitin-protein ligase synoviolin, Protein sel-1 homolog 1, Endoplasmic reticulum lectin 1, ... (6 entities in total)
• Functional Keywords: erad protein degradation, allergen
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 427394.36

Authors

Qian, H.W.,He, J.J. (deposition date: 2023-08-13, release date: 2025-02-19, Last modification date: 2025-09-03)

• Primary citation: Guo, L.,Liu, G.,He, J.,Jia, X.,He, Y.,Wang, Z.,Qian, H.; Structural insights into the human HRD1 ubiquitin ligase complex; Nat Commun, 16:6007-, 2025; DOI: 10.1038/s41467-025-61143-z

Experimental method

ELECTRON MICROSCOPY (3.5 Å)