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8KE7

Crystal structure of DNA binding and cleavage core of human topoisomerase 2-beta in a DNA binding-competent conformation

Summary for 8KE7
Entry DOI10.2210/pdb8ke7/pdb
DescriptorDNA topoisomerase 2-beta, ACETATE ION (3 entities in total)
Functional Keywordseukaryotic dna topoisomerase g-segment dna binding cleavage center assembly, dna binding protein
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight184388.13
Authors
Chan, N.L.,Liu, K.T.,Chen, S.F. (deposition date: 2023-08-11, release date: 2024-07-24)
Primary citationChan, N.L.,Liu, K.T.,Chen, S.F.
Structural Basis for the Assembly of Type IIA Topoisomerase DNA Cleavage/Religation Center
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

222926

数据于2024-07-24公开中

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