8KB4
Cryo-EM structure of human TMEM87A A308M
Summary for 8KB4
Entry DOI | 10.2210/pdb8kb4/pdb |
Related | 8HSI 8HTT |
EMDB information | 37069 |
Descriptor | Transmembrane protein 87A,EGFP, 2-acetamido-2-deoxy-beta-D-glucopyranose, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate (3 entities in total) |
Functional Keywords | non-selective cation channel, ion channel, membrane protein, golgi-localized protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 98128.72 |
Authors | |
Primary citation | Kang, H.,Han, A.R.,Zhang, A.,Jeong, H.,Koh, W.,Lee, J.M.,Lee, H.,Jo, H.Y.,Maria-Solano, M.A.,Bhalla, M.,Kwon, J.,Roh, W.S.,Yang, J.,An, H.J.,Choi, S.,Kim, H.M.,Lee, C.J. GolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory. Nat Commun, 15:5830-5830, 2024 Cited by PubMed: 38992057DOI: 10.1038/s41467-024-49297-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
Download full validation report