8KB4
Cryo-EM structure of human TMEM87A A308M
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Transmembrane protein 87A,EGFP | polymer | 854 | 96983.5 | 1 | UniProt (Q8NBN3) UniProt (A0A6M5E0N3) Pfam (PF21901) Pfam (PF06814) In PDB | Homo sapiens (human) | |
| 2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 3 | A | (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate | non-polymer | 481.6 | 1 | Chemie (65I) |
Sequence modifications
A: 1 - 555 (UniProt: Q8NBN3)
A: 577 - 814 (UniProt: A0A6M5E0N3)
| PDB | External Database | Details |
|---|---|---|
| Met 308 | Ala 308 | engineered mutation |
| Leu 556 | - | linker |
| Lys 557 | - | linker |
| Glu 558 | - | linker |
| Asn 559 | - | linker |
| Leu 560 | - | linker |
| Tyr 561 | - | linker |
| Phe 562 | - | linker |
| Gln 563 | - | linker |
| Gly 564 | - | linker |
| Asn 565 | - | linker |
| Pro 566 | - | linker |
| Ala 567 | - | linker |
| Phe 568 | - | linker |
| Leu 569 | - | linker |
| Tyr 570 | - | linker |
| Lys 571 | - | linker |
| Val 572 | - | linker |
| Val 573 | - | linker |
| Asp 574 | - | linker |
| Pro 575 | - | linker |
| Val 576 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gln 760 | His 185 | conflict |
| Glu 815 | - | expression tag |
| Phe 816 | - | expression tag |
| Leu 817 | - | expression tag |
| Val 818 | - | expression tag |
| Pro 819 | - | expression tag |
| Arg 820 | - | expression tag |
| Gly 821 | - | expression tag |
| Ser 822 | - | expression tag |
| Ser 823 | - | expression tag |
| Arg 824 | - | expression tag |
| Ser 825 | - | expression tag |
| Ala 826 | - | expression tag |
| Trp 827 | - | expression tag |
| Ser 828 | - | expression tag |
| His 829 | - | expression tag |
| Pro 830 | - | expression tag |
| Gln 831 | - | expression tag |
| Phe 832 | - | expression tag |
| Glu 833 | - | expression tag |
| Lys 834 | - | expression tag |
| Gly 835 | - | expression tag |
| Gly 836 | - | expression tag |
| Gly 837 | - | expression tag |
| Ser 838 | - | expression tag |
| Gly 839 | - | expression tag |
| Gly 840 | - | expression tag |
| Gly 841 | - | expression tag |
| Ser 842 | - | expression tag |
| Gly 843 | - | expression tag |
| Gly 844 | - | expression tag |
| Ser 845 | - | expression tag |
| Ala 846 | - | expression tag |
| Trp 847 | - | expression tag |
| Ser 848 | - | expression tag |
| His 849 | - | expression tag |
| Pro 850 | - | expression tag |
| Gln 851 | - | expression tag |
| Phe 852 | - | expression tag |
| Glu 853 | - | expression tag |
| Lys 854 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 96983.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1145.2 | |
| All* | Total formula weight | 98128.7 |
