8K68

Crystal structure of SARS-CoV-2 3CLpro M49K mutant

Summary for 8K68

Entry DOI	10.2210/pdb8k68/pdb
Descriptor	3C-like proteinase nsp5 (2 entities in total)
Functional Keywords	sars-cov-2 3clpro, mutant, wu-04, inhibitor, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
Total number of polymer chains	1
Total formula weight	33823.53
Authors	Zhang, L.J.,Hu, Q. (deposition date: 2023-07-25, release date: 2024-06-05)
Primary citation	Zhang, L.,Xie, X.,Luo, H.,Qian, R.,Yang, Y.,Yu, H.,Huang, J.,Shi, P.Y.,Hu, Q. Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04. Cell Discov, 10:40-40, 2024 Cited by PubMed: 38594245 DOI: 10.1038/s41421-024-00673-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation