8K60

Cryo-EM structure of Streptomyces coelicolor transcription initiation complex with the global transcription factor AfsR

Summary for 8K60

• Entry DOI: 10.2210/pdb8k60/pdb
• EMDB information: 36914
• Descriptor: DNA-directed RNA polymerase subunit alpha, ZINC ION, DNA-directed RNA polymerase subunit beta, ... (10 entities in total)
• Functional Keywords: transcription factor, transcription-dna complex, gene regulation
• Biological source: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145); More
• Total number of polymer chains: 11
• Total formula weight: 697769.12

Authors

Lin, W.,Shi, J. (deposition date: 2023-07-24, release date: 2024-07-31)

• Primary citation: Shi, J.,Ye, Z.,Feng, Z.,Wen, A.,Wang, L.,Zhang, Z.,Xu, L.,Song, Q.,Wang, F.,Liu, T.,Wang, S.,Feng, Y.,Lin, W.; Structural insights into transcription activation of the Streptomyces antibiotic regulatory protein, AfsR; Iscience, 27:110421-, 2024; DOI: 10.1016/j.isci.2024.110421

Experimental method

ELECTRON MICROSCOPY (3.4 Å)