8K3P
S. cerevisiae Chs1 in complex with polyoxin B
Summary for 8K3P
| Entry DOI | 10.2210/pdb8k3p/pdb |
| EMDB information | 36855 |
| Descriptor | Chitin synthase 1, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (2S)-2-[[(2S,3S,4S)-5-aminocarbonyloxy-2-azanyl-3,4-bis(oxidanyl)pentanoyl]amino]-2-[(2R,3S,4R,5R)-5-[5-(hydroxymethyl)-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]ethanoic acid (3 entities in total) |
| Functional Keywords | antifungal protein-inhibitor complex, antifungal protein/inhibitor |
| Biological source | Saccharomyces cerevisiae S288C |
| Total number of polymer chains | 2 |
| Total formula weight | 269149.71 |
| Authors | Bai, L.,Chen, D.D. (deposition date: 2023-07-16, release date: 2023-10-18, Last modification date: 2024-05-08) |
| Primary citation | Chen, D.D.,Wang, Z.B.,Wang, L.X.,Zhao, P.,Yun, C.H.,Bai, L. Structure, catalysis, chitin transport, and selective inhibition of chitin synthase. Nat Commun, 14:4776-4776, 2023 Cited by PubMed: 37553334DOI: 10.1038/s41467-023-40479-4 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.64 Å) |
Structure validation
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