8K2X
CXCR3-DNGi complex activated by CXCL10
Summary for 8K2X
Entry DOI | 10.2210/pdb8k2x/pdb |
EMDB information | 36842 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | g protein coupled receptor, chemokine receptor, cxcr3, cxcl10, complex, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 202299.74 |
Authors | Jiao, H.Z.,Hu, H.L. (deposition date: 2023-07-14, release date: 2023-11-29, Last modification date: 2023-12-13) |
Primary citation | Jiao, H.,Pang, B.,Chiang, Y.C.,Chen, Q.,Pan, Q.,Ren, R.,Hu, H. Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487. Cell Discov, 9:119-119, 2023 Cited by PubMed: 38012179DOI: 10.1038/s41421-023-00617-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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