8K2X

CXCR3-DNGi complex activated by CXCL10

8K2X の概要

• エントリーDOI: 10.2210/pdb8k2x/pdb
• EMDBエントリー: 36842
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• 機能のキーワード: g protein coupled receptor, chemokine receptor, cxcr3, cxcl10, complex, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 202299.74

構造登録者

Jiao, H.Z.,Hu, H.L. (登録日: 2023-07-14, 公開日: 2023-11-29, 最終更新日: 2025-07-16)

• 主引用文献: Jiao, H.,Pang, B.,Chiang, Y.C.,Chen, Q.,Pan, Q.,Ren, R.,Hu, H.; Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487.; Cell Discov, 9:119-119, 2023; PubMed: 38012179; DOI: 10.1038/s41421-023-00617-0

実験手法

ELECTRON MICROSCOPY (3.2 Å)