8JXU
Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition
Summary for 8JXU
Entry DOI | 10.2210/pdb8jxu/pdb |
EMDB information | 36713 |
Descriptor | ATP-binding cassette sub-family C member 2, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | atp-dependent transporter, conjugated organic anions transporter, atp hydrolyzes, transport protein, bilirubin, abc transporter |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 177923.66 |
Authors | Mao, Y.X.,Chen, Z.P.,Wang, L.,Hou, W.T.,Chen, Y.X.,Zhou, C.Z. (deposition date: 2023-07-01, release date: 2024-01-03, Last modification date: 2024-02-28) |
Primary citation | Mao, Y.X.,Chen, Z.P.,Wang, L.,Wang, J.,Zhou, C.Z.,Hou, W.T.,Chen, Y. Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15:1061-1061, 2024 Cited by PubMed: 38316776DOI: 10.1038/s41467-024-45337-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.55 Å) |
Structure validation
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