8JXU

Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition

8JXU の概要

• エントリーDOI: 10.2210/pdb8jxu/pdb
• EMDBエントリー: 36713
• 分子名称: ATP-binding cassette sub-family C member 2, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: atp-dependent transporter, conjugated organic anions transporter, atp hydrolyzes, transport protein, bilirubin, abc transporter
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 177923.66

構造登録者

Mao, Y.X.,Chen, Z.P.,Wang, L.,Hou, W.T.,Chen, Y.X.,Zhou, C.Z. (登録日: 2023-07-01, 公開日: 2024-01-03, 最終更新日: 2024-02-28)

• 主引用文献: Mao, Y.X.,Chen, Z.P.,Wang, L.,Wang, J.,Zhou, C.Z.,Hou, W.T.,Chen, Y.; Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.; Nat Commun, 15:1061-1061, 2024; PubMed: 38316776; DOI: 10.1038/s41467-024-45337-5

実験手法

ELECTRON MICROSCOPY (3.55 Å)