8JV7

Cryo-EM structure of the panda P2X7 receptor in complex with PPADS

8JV7 の概要

• エントリーDOI: 10.2210/pdb8jv7/pdb
• EMDBエントリー: 36670
• 分子名称: P2X purinoceptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(E)-[4-methanoyl-6-methyl-5-oxidanyl-3-(phosphonooxymethyl)pyridin-2-yl]diazenyl]benzene-1,3-disulfonic acid, ... (4 entities in total)
• 機能のキーワード: channel, transport protein
• 由来する生物種: Ailuropoda melanoleuca (giant panda)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 119010.08

構造登録者

Sheng, D.,Hattori, M. (登録日: 2023-06-27, 公開日: 2023-11-29, 最終更新日: 2024-05-15)

• 主引用文献: Sheng, D.,Yue, C.X.,Jin, F.,Wang, Y.,Ichikawa, M.,Yu, Y.,Guo, C.R.,Hattori, M.; Structural insights into the orthosteric inhibition of P2X receptors by non-ATP analog antagonists.; Elife, 12:-, 2024; PubMed: 38578670; DOI: 10.7554/eLife.92829

実験手法

ELECTRON MICROSCOPY (3.6 Å)