8JRE

Cryo-EM structure of a designed AAV8-based vector

This is a non-PDB format compatible entry.

Summary for 8JRE

• Entry DOI: 10.2210/pdb8jre/pdb
• EMDB information: 36594
• Descriptor: Capsid protein (1 entity in total)
• Functional Keywords: aav8, virus
• Biological source: Adeno-associated virus - 8
• Total number of polymer chains: 60
• Total formula weight: 3556211.46

Authors

Ke, X.,Luo, S.,Zheng, Q.,Jiang, H.,Liu, F.,Sun, X. (deposition date: 2023-06-16, release date: 2024-04-24, Last modification date: 2024-05-15)

• Primary citation: Luo, S.,Jiang, H.,Li, Q.,Qin, Y.,Yang, S.,Li, J.,Xu, L.,Gou, Y.,Zhang, Y.,Liu, F.,Ke, X.,Zheng, Q.,Sun, X.; An adeno-associated virus variant enabling efficient ocular-directed gene delivery across species.; Nat Commun, 15:3780-3780, 2024; PubMed: 38710714; DOI: 10.1038/s41467-024-48221-4

Experimental method

ELECTRON MICROSCOPY (2.08 Å)