8JQN

CryoEM structure of sNS1 complexed with Fab 2E11

Summary for 8JQN

• Entry DOI: 10.2210/pdb8jqn/pdb
• EMDB information: 36576
• Descriptor: 2E11 Fab Heavy Chain, 2E11 Fab Light Chain, Non-structural protein 1 (3 entities in total)
• Functional Keywords: zikv virus, non-structural protein 1, antibody, immune system, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 130892.99

Authors

Chen, Q.,Qi, P. (deposition date: 2023-06-14, release date: 2024-12-11)

• Primary citation: Pan, Q.,Xing, X.,Yu, J.,Chen, Q.,Jiao, H.,Zhang, W.,Wen, Y.,Gao, M.,Zhao, W.,Yu, L.,Hu, H.; Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1; Hlife, 2:527-541, 2024; DOI: 10.1016/j.hlife.2024.05.003

Experimental method

ELECTRON MICROSCOPY (2.8 Å)