8JNK

Crystal structure of human ALKBH3 bound to ssDNA through active site crosslink

Summary for 8JNK

• Entry DOI: 10.2210/pdb8jnk/pdb
• Descriptor: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, Synthetic antibody heavy chain, ... (7 entities in total)
• Functional Keywords: rna m1a demethylase, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 16
• Total formula weight: 302617.94

Authors

Zhang, L. (deposition date: 2023-06-06, release date: 2024-01-24, Last modification date: 2024-02-21)

• Primary citation: Zhang, L.,Duan, H.C.,Paduch, M.,Hu, J.,Zhang, C.,Mu, Y.,Lin, H.,He, C.,Kossiakoff, A.A.,Jia, G.,Zhang, L.; The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation.; Angew.Chem.Int.Ed.Engl., 63:e202313900-e202313900, 2024; PubMed: 38158383; DOI: 10.1002/anie.202313900

Experimental method

X-RAY DIFFRACTION (2.69 Å)