8JN8
Crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668
Summary for 8JN8
Entry DOI | 10.2210/pdb8jn8/pdb |
Descriptor | Proto-oncogene tyrosine-protein kinase Src, (2R)-N-cyclopentyl-2-[cyclopropyl(ethanoyl)amino]-2-(4-fluorophenyl)ethanamide (3 entities in total) |
Functional Keywords | src kinase, covalent inhibitor, auto-phosphorylation site, oncoprotein, oncoprotein-inhibitor complex, oncoprotein/inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 60304.94 |
Authors | |
Primary citation | Zhang, H.M.,Luo, C. The crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.902 Å) |
Structure validation
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