8JN8

Crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668

8JN8 の概要

• エントリーDOI: 10.2210/pdb8jn8/pdb
• 分子名称: Proto-oncogene tyrosine-protein kinase Src, (2R)-N-cyclopentyl-2-[cyclopropyl(ethanoyl)amino]-2-(4-fluorophenyl)ethanamide (3 entities in total)
• 機能のキーワード: src kinase, covalent inhibitor, auto-phosphorylation site, oncoprotein, oncoprotein-inhibitor complex, oncoprotein/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 60304.94

構造登録者

Zhang, H.M.,Luo, C. (登録日: 2023-06-06, 公開日: 2024-06-12)

• 主引用文献: Zhang, H.M.,Luo, C.; The crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668; To Be Published,

実験手法

X-RAY DIFFRACTION (1.902 Å)