8JKH

CryoEM structure of sNS1 complexed with Fab 4B8

Summary for 8JKH

• Entry DOI: 10.2210/pdb8jkh/pdb
• EMDB information: 36372
• Descriptor: NS1, the heavy chain of antibody 4B8, the light chain of antibody 4B8 (3 entities in total)
• Functional Keywords: zikv virus, non-structural protein 1, antibody, immune system, viral protein-immune system complex, viral protein/immune system
• Biological source: Zika virus; More
• Total number of polymer chains: 12
• Total formula weight: 259540.22

Authors

Chen, Q.,Pan, Q. (deposition date: 2023-06-01, release date: 2024-12-04)

• Primary citation: Pan, Q.,Xing, X.,Yu, J.,Chen, Q.,Jiao, H.,Zhang, W.,Wen, Y.,Gao, M.,Zhao, W.,Yu, L.,Hu, H.; Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1; Hlife, 2:527-541, 2024; DOI: 10.1016/j.hlife.2024.05.003

Experimental method

ELECTRON MICROSCOPY (2.64 Å)