8JFM

Crystal structure of enoyl-ACP reductase FabI in complex with NADH from Helicobacter pylori

Summary for 8JFM

• Entry DOI: 10.2210/pdb8jfm/pdb
• Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• Functional Keywords: enoyl-acp reductase, fabi, nadh, helicobacter pylori, biosynthetic protein
• Biological source: Helicobacter pylori
• Total number of polymer chains: 8
• Total formula weight: 243276.63

Authors

Song, W.Y.,Zhang, L. (deposition date: 2023-05-18, release date: 2023-11-15, Last modification date: 2023-11-22)

• Primary citation: Zhou, J.,Zhang, L.,Wang, Y.,Song, W.,Huang, Y.,Mu, Y.,Schmitz, W.,Zhang, S.Y.,Lin, H.,Chen, H.Z.,Ye, F.,Zhang, L.; The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis.; Angew.Chem.Int.Ed.Engl., 62:e202313109-e202313109, 2023; PubMed: 37779101; DOI: 10.1002/anie.202313109

Experimental method

X-RAY DIFFRACTION (2.21 Å)