8JCY
Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495, NAM563, and LY2389575 (dimerization mode I)
Summary for 8JCY
Entry DOI | 10.2210/pdb8jcy/pdb |
EMDB information | 36169 |
Descriptor | Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, Metabotropic glutamate receptor 3,Serine/threonine-protein kinase mTOR, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | complex structure, mglu2-3 heterodimer, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 225967.61 |
Authors | |
Primary citation | Wang, X.,Wang, M.,Xu, T.,Feng, Y.,Shao, Q.,Han, S.,Chu, X.,Xu, Y.,Lin, S.,Zhao, Q.,Wu, B. Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers. Cell Res., 33:762-774, 2023 Cited by PubMed: 37286794DOI: 10.1038/s41422-023-00830-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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