8JBO
Crystal structure of TxGH116 from Thermoanaerobacterium xylanolyticum with isofagomine
Summary for 8JBO
Entry DOI | 10.2210/pdb8jbo/pdb |
Related | 5BVU 5BX2 5BX3 5BX4 5BX5 |
Descriptor | Glucosylceramidase, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | txgh116, beta-glucosidase, acid/base mutant, thermoanaerobacterium xylanolyticum, cellobiose, hydrolase |
Biological source | Thermoanaerobacterium xylanolyticum LX-11 |
Total number of polymer chains | 2 |
Total formula weight | 185826.81 |
Authors | |
Primary citation | Meelua, W.,Thinkumrob, N.,Saparpakorn, P.,Pengthaisong, S.,Hannongbua, S.,Ketudat Cairns, J.R.,Jitonnom, J. Structural basis for inhibition of a GH116 beta-glucosidase and its missense mutants by GBA2 inhibitors: Crystallographic and quantum chemical study. Chem.Biol.Interact., 384:110717-110717, 2023 Cited by PubMed: 37726065DOI: 10.1016/j.cbi.2023.110717 PDB entries with the same primary citation |
Experimental method |
Structure validation
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