8JBF

Senktide bound to active human neurokinin 3 receptor in complex with Gq

8JBF の概要

• エントリーDOI: 10.2210/pdb8jbf/pdb
• EMDBエントリー: 36144
• 分子名称: Neuromedin-K receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ScFv16 nanobody, ... (6 entities in total)
• 機能のキーワード: g protein coupled receptor, neurokinin, cryo-em, peptide agonists, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 168538.77

構造登録者

Sun, W.J.,Yang, F.,Zhang, H.H.,Yuan, Q.N.,Yin, W.C.,Shi, P.,Eric, X.,Tian, C.L. (登録日: 2023-05-08, 公開日: 2024-02-28)

• 主引用文献: Sun, W.,Yang, F.,Zhang, H.,Yuan, Q.,Ling, S.,Wang, Y.,Lv, P.,Li, Z.,Luo, Y.,Liu, D.,Yin, W.,Shi, P.,Xu, H.E.,Tian, C.; Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists.; Cell Discov, 9:66-66, 2023; PubMed: 37391393; DOI: 10.1038/s41421-023-00564-w

実験手法

ELECTRON MICROSCOPY (3 Å)