8J7R

Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A (J-K-St/eIF4G focused)

Summary for 8J7R

• Entry DOI: 10.2210/pdb8j7r/pdb
• Related: 8HUJ
• EMDB information: 35041 36046
• Descriptor: Eukaryotic translation initiation factor 4 gamma 1, IRES RNA (J-K-St), MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: translation initiation factors, translation, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 66698.33

Authors

Suzuki, H.,Fujiyoshi, Y.,Imai, S.,Shimada, I. (deposition date: 2023-04-28, release date: 2023-08-02, Last modification date: 2023-09-13)

• Primary citation: Imai, S.,Suzuki, H.,Fujiyoshi, Y.,Shimada, I.; Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor.; Nat Commun, 14:4977-4977, 2023; PubMed: 37640715; DOI: 10.1038/s41467-023-40582-6

Experimental method

ELECTRON MICROSCOPY (3.7 Å)