8IT1
Cryo-EM structure of Crt-SPARTA-gRNA-tDNA tetramer (NADase active form)
Summary for 8IT1
Entry DOI | 10.2210/pdb8it1/pdb |
EMDB information | 35703 |
Descriptor | Piwi domain-containing protein, TIR domain-containing protein, DNA (45-mer), ... (4 entities in total) |
Functional Keywords | ago, dna/rna, tetramer, dna binding protein, dna binding protein-dna-rna complex, dna binding protein/dna/rna |
Biological source | Thermoflavifilum thermophilum More |
Total number of polymer chains | 16 |
Total formula weight | 528381.98 |
Authors | |
Primary citation | Gao, X.,Shang, K.,Zhu, K.,Wang, L.,Mu, Z.,Fu, X.,Yu, X.,Qin, B.,Zhu, H.,Ding, W.,Cui, S. Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625:822-831, 2024 Cited by PubMed: 37783228DOI: 10.1038/s41586-023-06665-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.41 Å) |
Structure validation
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