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8IT1

Cryo-EM structure of Crt-SPARTA-gRNA-tDNA tetramer (NADase active form)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, E, I, M)
Piwi domain-containing proteinpolymer50758304.84UniProt (A0A1I7NFD7)Thermoflavifilum thermophilumCrtAgo
2B, D, F, H
(B, F, J, N)
TIR domain-containing proteinpolymer45053256.74UniProt (A0A1I7NFG5)
Pfam (PF13676)
Thermoflavifilum thermophilumCrtTIR-APAZ
3I, K, M, O
(K, O, C, G)
DNA (45-mer)polymer4513721.94synthetic construct
4J, L, N, P
(L, P, D, H)
RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3')polymer216812.04synthetic construct
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains16
Total formula weight528382.0
All*Total formula weight528382.0
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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