8IS4
Structure of an Isocytosine specific deaminase Vcz in complexed with 5-FU
Summary for 8IS4
Entry DOI | 10.2210/pdb8is4/pdb |
Related | 7ww2 |
Descriptor | Hydroxydechloroatrazine ethylaminohydrolase, 5-FLUOROURACIL, ZINC ION, ... (6 entities in total) |
Functional Keywords | isocytosine, deaminase, vcz, 5-fu, hydrolase |
Biological source | Obesumbacterium proteus |
Total number of polymer chains | 2 |
Total formula weight | 99693.93 |
Authors | |
Primary citation | Guo, W.,Li, X.,Fan, J.,Li, H.,Wen, Y.,Meng, C.,Chen, H.,Zhao, Z.,Zhang, Y.,Du, Y.,Wu, B. Structural characterization of an isocytosine-specific deaminase VCZ reveals its application potential in the anti-cancer therapy. Iscience, 26:107672-107672, 2023 Cited by PubMed: 37680460DOI: 10.1016/j.isci.2023.107672 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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