8IQT

Crystal structure of the human vitamin D receptor ligand binding domain complexed with (23R)-F-25(OH)D3

Summary for 8IQT

• Entry DOI: 10.2210/pdb8iqt/pdb
• Related: 8IQN
• Descriptor: Vitamin D3 receptor, (1~{S},3~{Z})-3-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-1-[(2~{R},4~{R})-4-fluoranyl-6-methyl-6-oxidanyl-heptan-2-yl]-7~{a}-methyl-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol (3 entities in total)
• Functional Keywords: nuclear receptor, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 34820.60

Authors

Kakuda, S. (deposition date: 2023-03-17, release date: 2024-03-27)

• Primary citation: Kakuda, S.; Crystal structure of the human vitamin D receptor ligand binding domain complexed with (23R)-F-25(OH)D3; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.745 Å)