8ILU

Crystal structure of mouse Galectin-3 in complex with small molecule inhibitor

8ILU の概要

• エントリーDOI: 10.2210/pdb8ilu/pdb
• 分子名称: Galectin-3, (2R,3R,4R,5R,6S)-2-(hydroxymethyl)-6-[2-(2-methyl-1,3-benzothiazol-6-yl)-1,2,4-triazol-3-yl]-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol, THIOCYANATE ION, ... (5 entities in total)
• 機能のキーワード: fibrosis, galactose, sugar binding protein
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34109.92

構造登録者

Kumar, A.,Jinal, S.,Raman, S.,Ghosh, K. (登録日: 2023-03-04, 公開日: 2024-03-06)

• 主引用文献: Ghosh, K.; Identification of Benzothiazole Derived Monosaccharides as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3; To Be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)