8IL7

Structure of human soluble Adenylyl Cyclase in complex with lactate

Summary for 8IL7

Entry DOI	10.2210/pdb8il7/pdb
Descriptor	Adenylate cyclase type 10, (2S)-2-HYDROXYPROPANOIC ACID, GLYCEROL, ... (4 entities in total)
Functional Keywords	sac, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	54636.02
Authors	Li, Q.J.,Li, Z.L.,Gao, P. (deposition date: 2023-03-02, release date: 2023-07-26, Last modification date: 2024-08-14)
Primary citation	Liu, W.,Zhang, S.,Li, Q.,Wu, Y.,Jia, X.,Feng, W.,Li, Z.,Shi, Y.,Hou, Q.,Ma, J.,Liu, Y.,Gao, P.,Ganz, T.,Liu, S. Lactate modulates iron metabolism by binding soluble adenylyl cyclase. Cell Metab., 35:1597-1612.e6, 2023 Cited by PubMed: 37480842 DOI: 10.1016/j.cmet.2023.06.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation