8IC0
Cryo-EM structure of CXCL8 bound C-X-C chemokine receptor 1 in complex with Gi heterotrimer
Summary for 8IC0
Entry DOI | 10.2210/pdb8ic0/pdb |
EMDB information | 35351 |
Descriptor | C-X-C chemokine receptor type 1, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | gpcr, chemokine, interleukin, cxcr, membrane protein, membrane protein-immune system complex, membrane protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 163396.54 |
Authors | |
Primary citation | Ishimoto, N.,Park, J.H.,Kawakami, K.,Tajiri, M.,Mizutani, K.,Akashi, S.,Tame, J.R.H.,Inoue, A.,Park, S.Y. Structural basis of CXC chemokine receptor 1 ligand binding and activation. Nat Commun, 14:4107-4107, 2023 Cited by PubMed: 37433790DOI: 10.1038/s41467-023-39799-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.41 Å) |
Structure validation
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