8IA5

Small peptide enhances the binding of nutline-3a to N-terminal domain of MdmX

Summary for 8IA5

• Entry DOI: 10.2210/pdb8ia5/pdb
• Descriptor: Protein Mdm4, 9-mer peptide, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, ... (5 entities in total)
• Functional Keywords: mdmx, p53, nutlin-3a, enhancement, oncoprotein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 12191.95

Authors

Cheng, X.Y.,Wei, Q.Y.,Huang, Y.,Su, Z.D. (deposition date: 2023-02-07, release date: 2023-02-22, Last modification date: 2024-05-29)

• Primary citation: Cheng, X.Y.,Wei, Q.Y.,Huang, Y.,Su, Z.D.; Small peptide enhances the binding of nutline-3a to N-terminal domain of MdmX; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.93 Å)