8I5Z
LDH Mutant P101Q-(An unexpected single-point mutation triggers the unleashing of catalytic potential of a NADH-dependent dehydrogenase)
Summary for 8I5Z
| Entry DOI | 10.2210/pdb8i5z/pdb |
| Descriptor | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein (2 entities in total) |
| Functional Keywords | ldh, biosynthetic protein |
| Biological source | Thermodesulfatator indicus DSM 15286 |
| Total number of polymer chains | 4 |
| Total formula weight | 150845.19 |
| Authors | Liu, J.Q. (deposition date: 2023-01-26, release date: 2023-09-06, Last modification date: 2024-03-20) |
| Primary citation | Liu, J.,Liu, G.,Han, X.,Tao, F.,Xu, P. Characterization of the Pro101Gln mutation that enhances the catalytic performance of T. indicus NADH-dependent d-lactate dehydrogenase. Structure, 31:1616-1628.e3, 2023 Cited by PubMed: 37729918DOI: 10.1016/j.str.2023.08.019 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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