8I5Z

LDH Mutant P101Q-(An unexpected single-point mutation triggers the unleashing of catalytic potential of a NADH-dependent dehydrogenase)

8I5Z の概要

• エントリーDOI: 10.2210/pdb8i5z/pdb
• 分子名称: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein (2 entities in total)
• 機能のキーワード: ldh, biosynthetic protein
• 由来する生物種: Thermodesulfatator indicus DSM 15286
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 150845.19

構造登録者

Liu, J.Q. (登録日: 2023-01-26, 公開日: 2023-09-06, 最終更新日: 2024-03-20)

• 主引用文献: Liu, J.,Liu, G.,Han, X.,Tao, F.,Xu, P.; Characterization of the Pro101Gln mutation that enhances the catalytic performance of T. indicus NADH-dependent d-lactate dehydrogenase.; Structure, 31:1616-1628.e3, 2023; PubMed: 37729918; DOI: 10.1016/j.str.2023.08.019

実験手法

X-RAY DIFFRACTION (2.65 Å)