8HYK

CD-NTase EfCdnE in complex with intermediate pppU[2'-5']p

8HYK の概要

• エントリーDOI: 10.2210/pdb8hyk/pdb
• 分子名称: EfCdnE, [[(2R,3R,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: cd-ntase, cgas, cyclic dinucleotide, transferase
• 由来する生物種: Enterococcus faecalis EnGen0062
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36339.89

構造登録者

Ko, T.-P.,Wang, Y.-C.,Yang, C.-S.,Hou, M.-H.,Chen, Y. (登録日: 2023-01-06, 公開日: 2023-07-05, 最終更新日: 2023-09-13)

• 主引用文献: Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y.; Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.; Nat Commun, 14:5078-5078, 2023; PubMed: 37604815; DOI: 10.1038/s41467-023-40787-9

実験手法

X-RAY DIFFRACTION (2.021 Å)