8HYC

Crystal structure of B1 NDM-1 MBL in complex with 2-amino-5-(2-(thiophen-2-yl)ethyl)thiazole-4-carboxylic acid

Summary for 8HYC

• Entry DOI: 10.2210/pdb8hyc/pdb
• Descriptor: Metallo-beta-lactamase type 2, ZINC ION, 2-azanyl-5-(2-thiophen-2-ylethyl)-1,3-thiazole-4-carboxylic acid, ... (4 entities in total)
• Functional Keywords: beta-lactamase class b ndm-1, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 51919.83

Authors

Yan, Y.-H.,Zhu, K.-R.,Li, G.-B. (deposition date: 2023-01-06, release date: 2024-06-19)

• Primary citation: Yan, Y.-H.,Zhu, K.-R.,Yang, L.-L.,Li, G.-B.; 2-Aminothiazole-4-carboxylic acids as cross-class metallo-beta-lactamase inhibitors by mimicking beta-lactam hydrolysate binding; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.151 Å)