8HYB

Crystal structure of B1 IMP-1 MBL in complex with 2-amino-5-phenethylthiazole-4-carboxylic acid

Summary for 8HYB

• Entry DOI: 10.2210/pdb8hyb/pdb
• Descriptor: Beta-lactamase, ZINC ION, 2-azanyl-5-(2-phenylethyl)-1,3-thiazole-4-carboxylic acid, ... (6 entities in total)
• Functional Keywords: beta-lactamase class b imp-1, hydrolase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 4
• Total formula weight: 98671.25

Authors

Yan, Y.-H.,Zhu, K.-R.,Li, G.-B. (deposition date: 2023-01-06, release date: 2024-01-24)

• Primary citation: Yan, Y.-H.,Zhu, K.-R.,Yang, L.-L.,Li, G.-B.; 2-Aminothiazole-4-carboxylic acids as cross-class metallo-beta-lactamase inhibitors by mimicking beta-lactam hydrolysate binding; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.193 Å)