8HUG
F1 in complex with CRM1-Ran-RanBP1
Summary for 8HUG
Entry DOI | 10.2210/pdb8hug/pdb |
Descriptor | GTP-binding nuclear protein Ran, YRB1 isoform 1, CRM1 isoform 1, ... (10 entities in total) |
Functional Keywords | active ran, complex, transport protein, inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 157690.77 |
Authors | |
Primary citation | Li, C.,Zhang, Q.,Huang, W.,Huang, L.,Long, Q.,Lei, Y.,Jia, D.,Yang, S.,Yang, Y.,Zhang, X.,Sun, Q. Discovery of a Hidden Pocket beneath the NES Groove by Novel Noncovalent CRM1 Inhibitors. J.Med.Chem., 66:17044-17058, 2023 Cited by PubMed: 38105606DOI: 10.1021/acs.jmedchem.3c01867 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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