8HU5
Crystal structure of DNA octamer containing GuNA[Me,tBu]
Summary for 8HU5
| Entry DOI | 10.2210/pdb8hu5/pdb |
| Related | 8HIS |
| Descriptor | DNA (5'-D(*GP*(LR6)P*GP*(BRU)P*AP*CP*AP*C)-3') (2 entities in total) |
| Functional Keywords | dna, oligonucleotide, modified base, artificial nucleic acid |
| Biological source | synthetic construct |
| Total number of polymer chains | 1 |
| Total formula weight | 2630.69 |
| Authors | Aoyama, H.,Obika, H.,Yamaguchi, T. (deposition date: 2022-12-22, release date: 2023-08-09, Last modification date: 2023-09-06) |
| Primary citation | Yamaguchi, T.,Horie, N.,Aoyama, H.,Kumagai, S.,Obika, S. Mechanism of the extremely high duplex-forming ability of oligonucleotides modified with N-tert-butylguanidine- or N-tert-butyl-N'- methylguanidine-bridged nucleic acids. Nucleic Acids Res., 51:7749-7761, 2023 Cited by PubMed: 37462081DOI: 10.1093/nar/gkad608 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (0.93 Å) |
Structure validation
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