8HOY

Cryo-EM structure of monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex without DNA at 2.76 angostram

Summary for 8HOY

• Entry DOI: 10.2210/pdb8hoy/pdb
• EMDB information: 34684 34927
• Descriptor: DNA polymerase, DNA polymerase processivity factor component A20, E4R (3 entities in total)
• Functional Keywords: dna replication machinery, dna polymerase, b-family dna polymerase, uracil-dna glycosylase, mpxv, orthopoxvirus, poxviridae, dna processivity factor, viral protein
• Biological source: Monkeypox virus; More
• Total number of polymer chains: 3
• Total formula weight: 197128.79

Authors

Xu, Y.,Wu, Y.,Zhang, Y.,Fan, R.,Yang, Y.,Li, D.,Yang, B.,Zhang, Z.,Dong, C. (deposition date: 2022-12-11, release date: 2023-12-13, Last modification date: 2024-09-18)

• Primary citation: Xu, Y.,Wu, Y.,Zhang, Y.,Fan, R.,Yang, Y.,Li, D.,Zhu, S.,Yang, B.,Zhang, Z.,Dong, C.; Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex.; Cell Res., 33:479-482, 2023; PubMed: 36973539; DOI: 10.1038/s41422-023-00796-1

Experimental method

ELECTRON MICROSCOPY (2.76 Å)