8HOY

Cryo-EM structure of monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex without DNA at 2.76 angostram

8HOY の概要

• エントリーDOI: 10.2210/pdb8hoy/pdb
• EMDBエントリー: 34684 34927
• 分子名称: DNA polymerase, DNA polymerase processivity factor component A20, E4R (3 entities in total)
• 機能のキーワード: dna replication machinery, dna polymerase, b-family dna polymerase, uracil-dna glycosylase, mpxv, orthopoxvirus, poxviridae, dna processivity factor, viral protein
• 由来する生物種: Monkeypox virus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 197128.79

構造登録者

Xu, Y.,Wu, Y.,Zhang, Y.,Fan, R.,Yang, Y.,Li, D.,Yang, B.,Zhang, Z.,Dong, C. (登録日: 2022-12-11, 公開日: 2023-12-13, 最終更新日: 2025-07-02)

• 主引用文献: Xu, Y.,Wu, Y.,Zhang, Y.,Fan, R.,Yang, Y.,Li, D.,Zhu, S.,Yang, B.,Zhang, Z.,Dong, C.; Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex.; Cell Res., 33:479-482, 2023; PubMed: 36973539; DOI: 10.1038/s41422-023-00796-1

実験手法

ELECTRON MICROSCOPY (2.76 Å)