8HNM
CXCR3-DNGi complex activated by VUF11222
Summary for 8HNM
Entry DOI | 10.2210/pdb8hnm/pdb |
EMDB information | 34916 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | g protein coupled receptor, chemokine receptor, cxcr3, vuf11222, complex, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 192213.73 |
Authors | Jiao, H.Z.,Hu, H.L. (deposition date: 2022-12-08, release date: 2023-11-29, Last modification date: 2024-05-01) |
Primary citation | Jiao, H.,Pang, B.,Liu, A.,Chen, Q.,Pan, Q.,Wang, X.,Xu, Y.,Chiang, Y.C.,Ren, R.,Hu, H. Structural insights into the activation and inhibition of CXC chemokine receptor 3. Nat.Struct.Mol.Biol., 31:610-620, 2024 Cited by PubMed: 38177682DOI: 10.1038/s41594-023-01175-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.94 Å) |
Structure validation
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